I have someone you need to meet. I mean REALLY need to meet.
I met(saw) him at a lecture a few decades ago when I was attending a medical
conference in the Bay Area He is Bob Lustig MD, a professor and pediatric
endocrinologist who is starting to be noticed because of his health warnings of
excessive sugar and processed food consumption. His lecture to medical
students was my first exposure to the evils of sugar consumption. That is, the
evils of fructose consumption. Fructose is the evil twin of sucrose, table
sugar. Thus table sugar is about ½ glucose, AKA dextrose, and ½ fructose. I
will sketch out the damage that sugar, fast food and the gigantic processed
food industry has wrought upon the US and world population in the past 50 years.
Bob and his research group wrote an article in the NY Times in 2011 asking if
sugar was toxic? This was news to the world and created a furor in Big food and
big Ag and sugar industries who counter attacked fiercely.
Bo went on to
write a book called “Fat Chance” in 2013 and a companion volume “The Fat Chance
Cookbook.” I may review and refer to them as well but this review is for his latest
(2021) book entitled “Metabolical.”
If you want to
see the body shapes of America before our current epidemic of hypertension,
obesity and diabetes just turn on Turner classic movies of films from the 30’s
and 40’s such as “It’s a wonderful Life”. What do you see? NO FAT PEOPLE. Ok
maybe a few chubs and compare that to the folks you might see at the Atlanta
airport, a hub of America. It’s stunning. What happened to the US in the past 5
or 6 decades?
What happened is the “Metabolic
Syndrome.” I need to tell you that this
is a really terrible term which needs a better catchy name but we will have to
wait until someone comes up with a better moniker.
What you need to
know is that the Metabolic Syndrome is a collection or constellation of “diseases”
that are linked by a common thread of damage and dysfunction at the cellular
level and most notably at the mitochondria, that organelle inside every cell
that usually is referred to as the “powerhouse” of the cell. Those of you not well versed in physiology and
biochemistry may even now be struggling and thinking this book may not be for
you but you are wrong, with the emphasis on DEAD wrong.
Metabolic
Syndrome refers to what happens to the
body when fed the wrong food rather than
“Real Food”. Real food is what Michael Pollan referred to when he said it was
food that his grandmother would put on the table in the years before processed
food dominated food offerings. You can tell real food because it does not come
with an “ingredient list” or a food label. It is what grows in the ground and
on trees and bushes, what lays eggs and grazes on grass and swims and thrives in open unfettered water. It includes grains
and legumes and forbs consumed by people and animals. Anything else is not real food. Even wheat is
not real food if it only includes white flour from the endosperm of the wheat
berry. Whole wheat is only real food when it includes the bran and the wheat
germ as well as the endosperm which is mostly carbohydrate, some protein and a few micronutrients. This goes for all
the grains. If you grind up the wheat and throw away the bran and the wheat
germ, you are left with “processed” food.
Bob Lustig states repeatedly
that consumption of processed food and sugar is the cause of the Metabolic
syndrome which may affect as much as 88% of the American population. The
primary defect in metabolic syndrome is
at the cellular level and most specifically at eight processes within the cell
which go awry leading to improper and inappropriate routing of fat to the liver
and to visceral fat which lines your abdomen along with subcutaneous fat,” butt
fat”. It is associated with insulin
hypersecretion and insulin resistance. The most obvious manifestation is obesity.
Obesity may be a “symptom” of the metabolic
syndrome, a biomarker, if you will. Obesity associated with the metabolic
syndrome is not THE problem. Obesity of course can be a serious problem
associated with things like respiratory and orthopedic issues. Interestingly perhaps 20% of obese people do
not have metabolic syndrome and will live long and as much as 40% of thinner folks may have metabolic syndrome.
Metabolic syndrome includes hypertension and cardiovascular disease, type 2
diabetes and probably dementia as well as some autoimmune diseases such as
ankylosing spondylitis.
Accordingly it all
comes down to diet primarily and lack of exercise as the etiology of the
metabolic syndrome.
The real value of
the book is how and why we came to this terrible situation in which most of the
developed and developing world is unhealthy because of bad food.
Lustig lays out a long list of missteps and wrongheaded
policies at the governmental and corporate level starting with dust bowl
policies and terrible totally wrong recommendations such as the low fat
policies put into place by nutritionists misled by shoddy research from people
like Ancel Keys in the 70’s. Once industry started trying to market low fat
foods the population rebelled because the food tasted like cardboard. Industry’s
solution was to add sugar and salt and a variety of preservatives and other
chemicals to overcome eating cardboard. Society was also changing. Women were entering the
workforce and people felt that buying boxes and cans of processed and nearly
prepared food was so much easier than making their own meals from scratch. And
along came McDonalds and other fast food chains that did all the work and got
you in and out with a supersized double mac, giant order of fries and a 32 oz
coke for less than $6. Over 1200 calories for less than $6.
Lustig lays out
the list of villains and it is a long one indeed. They include doctors and
dentists and nutritionists and Big Pharma, big AG and feckless politicians whom
he names by name. The biggest
nutritional villain is sugar. Lustig presents data on sugar consumption which
was about 15 gm(3 tsp) a day after WW`1
and about 40 lbs per person/year in the “70s to 130 lbs(!!!) by 2010. An
important driver of this sugar consumption was soda , sports and energy drinks and fruit juices. A 32 oz soda from McDonalds
has 95 gm of sugar, 19 teaspoons!
Another telling statistic was that of the 600,000 foods in grocery stores over
80% have added sugar!
And it was not only sugar but lack of fiber
that was damaging our bodies. Removing fiber from foods damages the gut.
The trillions of “Good” bacteria in the large intestine need to be fed properly
to develop a healthy biome and it is fiber, both soluble and insoluble fiber
that feeds these beneficial critters. If you don’t feed the “good” bacteria
their proper diet of fiber you get an influx of “bad” bacteria which leads to
all manner of problems like “leaky gut” syndrome. The other important toxin is
fructose in sucrose and honey and maple syrup , agave and most especially high
fructose corn syrup, a chemically derived ultra cheap sweetener. The problem
with fructose toxicity is almost identical as the problem of alcohol toxicity
because fructose can only be metabolized in the liver and therein lies the
problem. The metabolites are aldehydes…think formaldehyde. Excess of alcohol
and fructose end up in the liver and visceral fat with terrible consequences
among which is inflammation. Fatty liver disease and alcoholic liver disease
may progress to inflammatory cirrhosis.
At this point I
need to tell the reader that Bob’s earlier book “Fat Chance” is an easier read
for the lay person . Metabolical has about 30 pages in Part 2 that I found extremely
useful and valuable to a detailed understanding of metabolic syndrome. But a
disclaimer here: I am a doctor who studied biochemistry and physiology and I
majored in chemistry. If you didn’t, you may find this dense and
incomprehensible. In fact Bob even suggest skipping over it to his excellent recommendations
of how to self diagnose and discuss this intelligently with your physician . I think
that is fine but I do suggest the reader trying to understand the disease at
the cellular level and if necessary come back to review or seek other sources
in books or on youtube.
One of the more
interesting sections of the book dealt with the addictive properties of sugar
and other additives to fast and processed food such as caffeine and Lustig makes
an analogy with the crimes of the Tobacco industry doctoring nicotine content
to increase addictive properties. He also goes to great length to describe why
all these chemicals and additions and subtractions to food are done which has
mostly to do with stability and shelf life. Recall the stories of 30 year old
Twinkies!
He also discusses at some length what diets
exist and why some are better than others at ameliorating metabolic syndrome.
It’s not all good news. Some of the depressing revelations have to do with the
concept of epigenetics in which the dietary missteps of a pregnant mother
influence the health and long term outcome of her fetus. Allowing children
unfettered access to sweets and horrible foods like sweetened morning cereals
can doom a child not only to cavities but to long term sugar dependence. Once a person has loaded up his liver and visceral
fat and arteries, removing it can prove very difficult to reverse.
I will let the
reader draw his or her own conclusions upon understanding the value of real
food and avoiding consumption of “unreal” food.
Over the past decade we have made changes to our diet and now eat almost
entirely real food such as grinding our own grains, raising our own livestock
and poultry that graze on grass, eating wild game and having large gardens.
This can be difficult for urban apartment dwellers but most of us have access
to farmers markets where you can look the farmer in the eye. Get used to it.
Real food costs more. Processed food and
fast food which I call “fast garbage” is cheap and subsidized and convenient if
you are by nature lazy.
Real food is the key
to combating the metabolic syndrome. And don’t forget exercise. Exercise is a
lousy way to lose weight and if that is the only reason you do it, you will be
sorely disappointed. Regular exercise generates increased production of
mitochondria, lowers serum cortisol, aids your sleep, diminishes stress and if
you’re lucky gives you doses of endorphins, your runner’s high.
There is one thing
which Robert Lustig gave in his detailed
recommendations in both books which I found particularly useful. He divides
food into 3 colors: red foods, yellow foods and green foods. Red foods might be
that big slab of chocolates cake slathered with ice cream which you can have
occasionally, even once a week. Yellow foods are foods such as potatoes or
white flour pasta, high carbohydrates maybe 2 or 3 times a week and green foods
are almost all fruits and vegetables eggs and whole grains to consume anytime and often. Lustig
does not specifically mention foods I would call “black foods” which
should never be consumed but it is tacitly there all through his book if you
read between the lines. Never NEVER drink sodas or sweetened drinks or any
fruit juices. Oranges and apples, yes. Orange and apple juice juice, never. The
fiber in the fruit is the antidote to the fructose. And renounce all fast food
outlets. Avoid them like the plague.
Finally Bob lists
what can be done to combat the giant industries on a political level who have been willfully
destroying public health and that of course is enacting laws and issuing fines
to the culprits much like what was done to big tobacco. That means laws and of
this I am less sanguine. I live in a wonderful state full of libertarians
suspicious of the “nanny state” who want to issue laws restricting your
freedoms like taking away your guns and now your sugar! I think a more
realistic strategy is educating the public that sugar is a poison in large amounts.
Use a little occasionally and if it is in the ingredient list on the box, just
put it back on the shelf.
I have just a tiny
quibble with Bob’s sugar as a poison concept.It is the fructose that is the
real poison. If you simply must have some sweet in your life, substitute
Glucose, commonly known as dextrose. It is expensive in small quantities and so
we buy it bulk in 50 lb sacks which can be obtained online or in places like
brewer supply stores. If the recipe call for sucrose and you don’t want to give
up the yummy tang of molasses or brown sugar, try using only 50% sucrose and
using dextrose for the other 50%. If we
bake sweets, that is how we use sugar. BTW, Karo corn syrup is pure liquid
dextrose.
Bob mentions in his book that people’s attitudes can change and prohibitions enacted.
MADD have sut drunk driving accidents way down. Seat belts in cars were ignored
and ridiculed and now who would climb in a gar without snapping on their belt.
Even trans fats were in all bakery goods and are now gone. If you value your
health and those you love you must read this book. Now that Bob is retired he
is finding time for interviews with people like Nate Hagens on Youtube.
